The angiogenic factors and their soluble receptors in sepsis: friend, foe, or both?

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The angiogenic factors and their soluble receptors in sepsis: friend, foe, or both?

The endothelium represents an important source of, and a target for, inflammation in sepsis. Angiogenic factors and their receptors, including vascular endothelial growth factor (VEGF)/VEGF receptor and the angiopoietin/Tie2 signaling pathways, have recently received great attention in critically ill patients, including those with sepsis [1-3], because of their pivotal roles in both angiogenesi...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2013

ISSN: 1364-8535

DOI: 10.1186/cc12857